China launched its first Mars mission in 2020 and is scheduling a sample return mission in 2028. Such deep space missions require high-precision Earth–Mars radio tracking. However, Corotating Interaction Regions (CIRs) in the solar wind can pose considerable influence on the radio link. This study constructs a CIR density model embedded within a quiescent solar wind background, assuming a solar rotation period of 26 days. We integrate the plasma density along the line-of-sight over two three-year spans (2020.07—2023.07 and 2029.01—2032.01) to simulate periodic CIR crossings. Results indicate that CIR-induced Total Electron Content (TEC) enhancements fluctuate between 40 TECU at Mars opposition and 330 TECU, a pattern primarily dictated by the 26 month planetary synodic cycle. The most significant link impairments are projected for 2021 January–July and 2029 June–2030 February, periods which conversely offer optimal geometries for radio sounding of CIR structures. Given that multiple CIRs may intersect the ray path simultaneously, their cumulative delays must be integrated into future navigation models to safeguard mission accuracy.