Based on the spectral data from the LAMOST Medium-Resolution Spectroscopic Survey (LAMOST-MRS) DR11-v1.1, combined with a publicly available open cluster catalog, we built a large-sample database of open clusters with medium-resolution spectroscopic parameters. This sample encompasses radial velocity measurements from medium-resolution spectroscopy for 1033 open clusters, among which 446 clusters further offer metallicity profiles and abundance distributions for dozens of chemical elements. Based on this comprehensive data set, we performed statistical analyses on key parameters of open clusters, including radial velocities, metallicities, and chemical element abundances. Notably, when the star cluster radial velocities are compared with results from the high-resolution spectroscopic survey, the mean difference is constrained within 1 km s−1, with a standard deviation less than 10 km s−1. For metallicity [Fe/H] comparisons with published high-resolution literature values, the average discrepancy falls in the range of 0.02–0.04 dex, accompanied by a standard deviation of 0.06–0.08 dex. These findings demonstrate that open cluster properties derived by LAMOST-MRS exhibit reliable precision, making them suitable as probes for in-depth investigations into the chemical evolution of the Milky Way. Finally, we have compiled a catalog of 1033 open clusters, complemented by parameter lists for approximately 7000 member stars—all including their LAMOST-MRS spectroscopic parameters. This data set provides a valuable resource for advancing galactic astrophysics research.