This study presents a comprehensive end-to-end simulation analysis of the optical imaging performance of the Chinese Space Station Survey Telescope (CSST) under in-orbit conditions. An integrated system model incorporating five static and two dynamic error sub-models was established. Wave front errors were calculated for each sub-model and compared to the integrated system error to quantify the individual contributions to image degradation. At the detector level, wave front error, point-spread function (PSF), and ellipticity were evaluated across the full field of view (FOV). The average radius of 80% encircled energy (REE80) of the PSF under full-error conditions was determined for 25 field points, yielding a value of 0″.114. Furthermore, the calculations indicate a correlation between the wave front distribution and the ellipticity distribution within the optical system. By optimizing the wave front distribution, it is possible to adjust the ellipticity distribution of the PSF across the full FOV. The end-to-end simulation approach adopted in this paper provides a theoretical foundation for improving the image quality in large-aperture, off-axis space telescopes.

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