The Mini-SiTian project, which is a pathfinder for the SiTian project, utilizes three 30 cm telescopes equipped with commercial CMOS cameras (ZWOASI6200MM Pro) to simulate a large-area time-domain survey. Due to the avoidance of the traditional mechanical shutter, the CMOS camera is favorable in time-domain survey projects. In the future, the SiTian telescope array will employ a two-by-two scientific-grade mosaic CMOS camera to survey a 10,000 degree square area every 30 minutes. Therefore, the performance of CMOS directly determines the detection capability of SiTian telescopes for transient sources, and a comprehensive understanding of the performance of CMOS cameras is crucial. In this research, laboratory testing was conducted to thoroughly evaluate three cameras by assessing several critical parameters, including bias stability, dark current, pixel anomalies, linearity, gain, and read noise. We find exceptional short-term bias stability with standard deviations below 0.02 ADU, negligible dark current of approximately 0.002 e− pixel−1 s−1 at 0°C, and excellent linearity with nonlinearity consistently below ±0.5%, and a small proportion (0.06%–0.08%) of pixels with anomalous responses. Furthermore, our analysis demonstrates uniform gain values across all cameras, ranging from 0.252 to 0.255 e− ADU−1, with low readout noise, measured to be below 1.6 e− using conventional methods. We also propose a novel method for pixel-level gain and read noise calculation for CMOS sensors, which revealed a narrow gain distribution and a low median read noise of 1.028 e− for one of the cameras. The laboratory testing of the ZWOASI6200MM Pro cameras indicates their potential to meet the requirements of time-domain surveys for the Mini-SiTian project.