Active adjustment technology is used to solve the problem of reduced electrical performance of large reflector antennas caused by environmental factors. This technology is crucial for the operation of antennas under high-frequency working conditions. This paper proposes a full-path active adjustment strategy for dual-reflector antennas. This strategy takes into account the working mode of the adjustment mechanism under comprehensive influencing factors and achieves the optimal receiving performance at the full elevation by changing different adjustment algorithms. First, the relationship between the displacement of reflector and the wavefront phase was established based on geometric optics. Second, three adjustment algorithms of the double reflector antenna were compared and analyzed: based on the standard, the fit and the optimal parabolic surface, the calculation process of the adjustment amount was derived. An adjustment strategy model for multiple working conditions was proposed by introducing the elevation and the complexity coefficient and combining three adjustment algorithms. Finally, a finite element analysis was conducted on the dual-reflector antenna with a diameter of 110 m, and the advantages and disadvantages of different adjustment algorithms were compared. The results show that strategy model not only achieves the optimal state of the antenna at the full elevation, but also shortens the adjustment amount of the adjustment mechanism and improves the working efficiency of the antenna under various working conditions.